Comparative effectiveness, safety and acceptability of medical abortion at home and in a clinic: a systematic review

Comparative effectiveness, safety and acceptability of medical abortion at home and in a clinic: a systematic review

Blog Article

OBJECTIVE: To compare medical abortion practised at home and in clinics in terms of effectiveness, safety and acceptability.METHODS: A systematic search for randomized controlled trials and prospective cohort studies comparing home-based and clinic-based medical abortion was conducted.The Cochrane Central Register of Controlled Trials, EMBASE, MEDLINE and Popline were searched.Failure to abort completely, side-effects and acceptability were Floor Stickers the main outcomes of interest.Odds ratios and their 95% confidence intervals (CIs) were calculated.

Estimates were pooled using a random-effects model.FINDINGS: Nine studies met the inclusion criteria (n = 4522 participants).All were prospective cohort studies that used mifepristone and misoprostol to induce abortion.Complete abortion was achieved by 86-97% of the women who underwent home-based abortion (n = 3478) and by 80-99% of those who underwent clinic-based abortion (n = 1044).Pooled analyses from all studies revealed no difference in complete abortion rates between groups (odds ratio = 0.

8; 95% CI: 0.5-1.5).Serious complications from abortion were rare.Pain and vomiting lasted 0.

3 days longer among women who took misoprostol at home rather than in clinic.Women who chose home-based medical abortion were more likely to be satisfied, to choose the method again and to recommend it to a friend than women who opted for medical abortion in a clinic.CONCLUSION: Home-based abortion is safe under the conditions in place in the included studies.Prospective cohort studies have shown no differences in effectiveness or acceptability between home-based and clinic-based medical abortion ORG PINEAPPLE CHUNKS across countries.